{"id":4792,"date":"2025-05-21T14:46:56","date_gmt":"2025-05-21T17:46:56","guid":{"rendered":"https:\/\/mbinitiative.org\/?p=4792"},"modified":"2025-05-22T20:17:29","modified_gmt":"2025-05-22T23:17:29","slug":"clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer","status":"publish","type":"post","link":"https:\/\/mbinitiative.org\/pt\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/","title":{"rendered":"Ensaio cl\u00ednico com terapia inovadora come\u00e7a a tratar crian\u00e7as com c\u00e2ncer"},"content":{"rendered":"<p>Neste m\u00eas de maio de 2025, as primeiras crian\u00e7as com meduloblastoma receberam o tratamento experimental do estudo MATCHPOINT, representando um avan\u00e7o sem precedentes financiado pela MBI. Enquanto os primeiros pacientes iniciam a terapia, novas crian\u00e7as e jovens adultos com meduloblastoma recidivado ou refrat\u00e1rio continuam sendo recrutados para o ensaio cl\u00ednico nos EUA.<\/p>\n\n\n\n<p>Aprovado pelo FDA em 2024, o estudo iniciou em mar\u00e7o e agora avan\u00e7a, acompanhando doze pacientes por dois anos - oferecendo esperan\u00e7a concreta para casos que at\u00e9 ent\u00e3o n\u00e3o possu\u00edam op\u00e7\u00f5es terap\u00eauticas eficazes.<\/p>\n\n\n\n<p>A abordagem combina c\u00e9lulas T modificadas com ativadores imunol\u00f3gicos, 'ensinando' o sistema imunol\u00f3gico a combater o tumor com precis\u00e3o.<em>\u201cUm avan\u00e7o inimagin\u00e1vel h\u00e1 tr\u00eas anos<\/em>\", destaca Fernando Goldsztein, fundador da MBI.<\/p>\n\n\n\n<p>Para saber mais sobre o ensaio e recrutamento,<a href=\"https:\/\/clinicaltrials.gov\/study\/NCT06514898?cond=Medulloblastoma&amp;aggFilters=status:not%20rec&amp;page=2&amp;rank=14\"> clique aqui<\/a>.<br><\/p>\n\n\n\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>In May 2025, the first children with medulloblastoma received the experimental treatment in the MATCHPOINT study, representing an unprecedented breakthrough funded by MBI. While these initial patients begin therapy, new pediatric and young adult participants with recurrent or refractory medulloblastoma continue to be recruited for the clinical trial in the U.S. FDA-approved in 2024, the [&hellip;]<\/p>","protected":false},"author":4,"featured_media":4820,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-4792","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sem-categoria"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Clinical trial with innovative therapy begins treating children with cancer - The Medulloblastoma Initiative<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mbinitiative.org\/pt\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Clinical trial with innovative therapy begins treating children with cancer - The Medulloblastoma Initiative\" \/>\n<meta property=\"og:description\" content=\"In May 2025, the first children with medulloblastoma received the experimental treatment in the MATCHPOINT study, representing an unprecedented breakthrough funded by MBI. While these initial patients begin therapy, new pediatric and young adult participants with recurrent or refractory medulloblastoma continue to be recruited for the clinical trial in the U.S. FDA-approved in 2024, the [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mbinitiative.org\/pt\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/\" \/>\n<meta property=\"og:site_name\" content=\"The Medulloblastoma Initiative\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/themedulloblastomainitiative\" \/>\n<meta property=\"article:published_time\" content=\"2025-05-21T17:46:56+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-05-22T23:17:29+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mbinitiative.org\/wp-content\/uploads\/2025\/05\/Design-sem-nome-1-1.png\" \/>\n\t<meta property=\"og:image:width\" content=\"908\" \/>\n\t<meta property=\"og:image:height\" content=\"512\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"MBI\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"MBI\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. tempo de leitura\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/\"},\"author\":{\"name\":\"MBI\",\"@id\":\"https:\/\/mbinitiative.org\/#\/schema\/person\/466abe8aeac08de69ff51a723b647b7f\"},\"headline\":\"Clinical trial with innovative therapy begins treating children with cancer\",\"datePublished\":\"2025-05-21T17:46:56+00:00\",\"dateModified\":\"2025-05-22T23:17:29+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/\"},\"wordCount\":134,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/mbinitiative.org\/#organization\"},\"image\":{\"@id\":\"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/mbinitiative.org\/wp-content\/uploads\/2025\/05\/Design-sem-nome-1-1.png\",\"inLanguage\":\"pt-BR\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/\",\"url\":\"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/\",\"name\":\"Clinical trial with innovative therapy begins treating children with cancer - The Medulloblastoma Initiative\",\"isPartOf\":{\"@id\":\"https:\/\/mbinitiative.org\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/mbinitiative.org\/wp-content\/uploads\/2025\/05\/Design-sem-nome-1-1.png\",\"datePublished\":\"2025-05-21T17:46:56+00:00\",\"dateModified\":\"2025-05-22T23:17:29+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/#breadcrumb\"},\"inLanguage\":\"pt-BR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/#primaryimage\",\"url\":\"https:\/\/mbinitiative.org\/wp-content\/uploads\/2025\/05\/Design-sem-nome-1-1.png\",\"contentUrl\":\"https:\/\/mbinitiative.org\/wp-content\/uploads\/2025\/05\/Design-sem-nome-1-1.png\",\"width\":908,\"height\":512},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"In\u00edcio\",\"item\":\"https:\/\/mbinitiative.org\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Clinical trial with innovative therapy begins treating children with cancer\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/mbinitiative.org\/#website\",\"url\":\"https:\/\/mbinitiative.org\/\",\"name\":\"The Medulloblastoma Initiative\",\"description\":\"Cura do Meduloblastoma Infantil\",\"publisher\":{\"@id\":\"https:\/\/mbinitiative.org\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/mbinitiative.org\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"pt-BR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/mbinitiative.org\/#organization\",\"name\":\"The Medulloblastoma Initiative\",\"url\":\"https:\/\/mbinitiative.org\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\/\/mbinitiative.org\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/mbinitiative.org\/wp-content\/uploads\/2023\/10\/LOGO-MBI.png\",\"contentUrl\":\"https:\/\/mbinitiative.org\/wp-content\/uploads\/2023\/10\/LOGO-MBI.png\",\"width\":354,\"height\":168,\"caption\":\"The Medulloblastoma Initiative\"},\"image\":{\"@id\":\"https:\/\/mbinitiative.org\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/themedulloblastomainitiative\",\"https:\/\/www.instagram.com\/medulloblastomainitiative\/\",\"https:\/\/www.linkedin.com\/company\/medulloblastomainitiative\/\",\"https:\/\/www.youtube.com\/@mbinitiative\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/mbinitiative.org\/#\/schema\/person\/466abe8aeac08de69ff51a723b647b7f\",\"name\":\"MBI\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\/\/mbinitiative.org\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/6446aa8591e99bf1553d89bc19db5af72fd25b4c6593ea37fd3dae05f7f06bb2?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/6446aa8591e99bf1553d89bc19db5af72fd25b4c6593ea37fd3dae05f7f06bb2?s=96&d=mm&r=g\",\"caption\":\"MBI\"},\"url\":\"https:\/\/mbinitiative.org\/pt\/author\/mbi\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Clinical trial with innovative therapy begins treating children with cancer - The Medulloblastoma Initiative","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/mbinitiative.org\/pt\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/","og_locale":"pt_BR","og_type":"article","og_title":"Clinical trial with innovative therapy begins treating children with cancer - The Medulloblastoma Initiative","og_description":"In May 2025, the first children with medulloblastoma received the experimental treatment in the MATCHPOINT study, representing an unprecedented breakthrough funded by MBI. While these initial patients begin therapy, new pediatric and young adult participants with recurrent or refractory medulloblastoma continue to be recruited for the clinical trial in the U.S. FDA-approved in 2024, the [&hellip;]","og_url":"https:\/\/mbinitiative.org\/pt\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/","og_site_name":"The Medulloblastoma Initiative","article_publisher":"https:\/\/www.facebook.com\/themedulloblastomainitiative","article_published_time":"2025-05-21T17:46:56+00:00","article_modified_time":"2025-05-22T23:17:29+00:00","og_image":[{"width":908,"height":512,"url":"https:\/\/mbinitiative.org\/wp-content\/uploads\/2025\/05\/Design-sem-nome-1-1.png","type":"image\/png"}],"author":"MBI","twitter_card":"summary_large_image","twitter_misc":{"Escrito por":"MBI","Est. tempo de leitura":"1 minuto"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/#article","isPartOf":{"@id":"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/"},"author":{"name":"MBI","@id":"https:\/\/mbinitiative.org\/#\/schema\/person\/466abe8aeac08de69ff51a723b647b7f"},"headline":"Clinical trial with innovative therapy begins treating children with cancer","datePublished":"2025-05-21T17:46:56+00:00","dateModified":"2025-05-22T23:17:29+00:00","mainEntityOfPage":{"@id":"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/"},"wordCount":134,"commentCount":0,"publisher":{"@id":"https:\/\/mbinitiative.org\/#organization"},"image":{"@id":"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/#primaryimage"},"thumbnailUrl":"https:\/\/mbinitiative.org\/wp-content\/uploads\/2025\/05\/Design-sem-nome-1-1.png","inLanguage":"pt-BR","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/","url":"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/","name":"Clinical trial with innovative therapy begins treating children with cancer - The Medulloblastoma Initiative","isPartOf":{"@id":"https:\/\/mbinitiative.org\/#website"},"primaryImageOfPage":{"@id":"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/#primaryimage"},"image":{"@id":"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/#primaryimage"},"thumbnailUrl":"https:\/\/mbinitiative.org\/wp-content\/uploads\/2025\/05\/Design-sem-nome-1-1.png","datePublished":"2025-05-21T17:46:56+00:00","dateModified":"2025-05-22T23:17:29+00:00","breadcrumb":{"@id":"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/#breadcrumb"},"inLanguage":"pt-BR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/"]}]},{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/#primaryimage","url":"https:\/\/mbinitiative.org\/wp-content\/uploads\/2025\/05\/Design-sem-nome-1-1.png","contentUrl":"https:\/\/mbinitiative.org\/wp-content\/uploads\/2025\/05\/Design-sem-nome-1-1.png","width":908,"height":512},{"@type":"BreadcrumbList","@id":"https:\/\/mbinitiative.org\/clinical-trial-with-innovative-therapy-begins-treating-children-with-cancer\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"In\u00edcio","item":"https:\/\/mbinitiative.org\/"},{"@type":"ListItem","position":2,"name":"Clinical trial with innovative therapy begins treating children with cancer"}]},{"@type":"WebSite","@id":"https:\/\/mbinitiative.org\/#website","url":"https:\/\/mbinitiative.org\/","name":"(The Medulloblastoma Initiative)","description":"Cura do Meduloblastoma Infantil","publisher":{"@id":"https:\/\/mbinitiative.org\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/mbinitiative.org\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"pt-BR"},{"@type":"Organization","@id":"https:\/\/mbinitiative.org\/#organization","name":"(The Medulloblastoma Initiative)","url":"https:\/\/mbinitiative.org\/","logo":{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/mbinitiative.org\/#\/schema\/logo\/image\/","url":"https:\/\/mbinitiative.org\/wp-content\/uploads\/2023\/10\/LOGO-MBI.png","contentUrl":"https:\/\/mbinitiative.org\/wp-content\/uploads\/2023\/10\/LOGO-MBI.png","width":354,"height":168,"caption":"The Medulloblastoma Initiative"},"image":{"@id":"https:\/\/mbinitiative.org\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/themedulloblastomainitiative","https:\/\/www.instagram.com\/medulloblastomainitiative\/","https:\/\/www.linkedin.com\/company\/medulloblastomainitiative\/","https:\/\/www.youtube.com\/@mbinitiative"]},{"@type":"Person","@id":"https:\/\/mbinitiative.org\/#\/schema\/person\/466abe8aeac08de69ff51a723b647b7f","name":"MBI","image":{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/mbinitiative.org\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/6446aa8591e99bf1553d89bc19db5af72fd25b4c6593ea37fd3dae05f7f06bb2?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/6446aa8591e99bf1553d89bc19db5af72fd25b4c6593ea37fd3dae05f7f06bb2?s=96&d=mm&r=g","caption":"MBI"},"url":"https:\/\/mbinitiative.org\/pt\/author\/mbi\/"}]}},"_links":{"self":[{"href":"https:\/\/mbinitiative.org\/pt\/wp-json\/wp\/v2\/posts\/4792","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mbinitiative.org\/pt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mbinitiative.org\/pt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mbinitiative.org\/pt\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/mbinitiative.org\/pt\/wp-json\/wp\/v2\/comments?post=4792"}],"version-history":[{"count":1,"href":"https:\/\/mbinitiative.org\/pt\/wp-json\/wp\/v2\/posts\/4792\/revisions"}],"predecessor-version":[{"id":4794,"href":"https:\/\/mbinitiative.org\/pt\/wp-json\/wp\/v2\/posts\/4792\/revisions\/4794"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mbinitiative.org\/pt\/wp-json\/wp\/v2\/media\/4820"}],"wp:attachment":[{"href":"https:\/\/mbinitiative.org\/pt\/wp-json\/wp\/v2\/media?parent=4792"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mbinitiative.org\/pt\/wp-json\/wp\/v2\/categories?post=4792"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mbinitiative.org\/pt\/wp-json\/wp\/v2\/tags?post=4792"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}