{"id":192,"date":"2023-10-02T16:45:59","date_gmt":"2023-10-02T19:45:59","guid":{"rendered":"http:\/\/an1-homologacao.com.br\/?page_id=192"},"modified":"2025-10-29T15:06:29","modified_gmt":"2025-10-29T18:06:29","slug":"rede-de-pesquisa-2","status":"publish","type":"page","link":"https:\/\/mbinitiative.org\/pt\/rede-de-pesquisa-2\/","title":{"rendered":"Research Network"},"content":{"rendered":"
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REDE DE PESQUISA<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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A busca pela<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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cura<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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POR QUE O TRABALHO DA MBI FAZ TANTA DIFEREN\u00c7A<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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O meduloblastoma \u00e9 o c\u00e2ncer cerebral mais comum em crian\u00e7as e representa, globalmente, quase um quinto de todos os tumores cerebrais na inf\u00e2ncia.<\/p>

Por\u00e9m, \u00e9 dif\u00edcil obter recursos para a pesquisa em meduloblastoma, porque o c\u00e2ncer em crian\u00e7as \u2014 qualquer tipo de c\u00e2ncer \u2014 \u00e9 considerado uma doen\u00e7a \u201crara\u201d, j\u00e1 que o n\u00famero de crian\u00e7as afetadas \u00e9 menor se comparado ao n\u00famero de adultos com c\u00e2ncer.\n
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\nEssa lacuna de financiamento gera uma situa\u00e7\u00e3o de \u201cquem vem primeiro, o ovo ou a galinha\u201d: sem recursos, \u00e9 muito dif\u00edcil testar e criar novos modelos para entender as bases da doen\u00e7a; por\u00e9m, sem esses modelos, \u00e9 dif\u00edcil obter financiamento de \u00f3rg\u00e3os financiadores de pesquisa (como os Institutos Nacionais de Sa\u00fade ou o Instituto Nacional do C\u00e2ncer nos EUA).<\/p>

Menos pesquisa em c\u00e2ncer pedi\u00e1trico significa tratamentos mais t\u00f3xicos, mais efeitos adversos e, em alguns casos, poucas chances de sobreviver. E \u00e9 a\u00ed que entra o trabalho da MBI.<\/strong><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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A \u00fanica maneira de encontrar a cura para o meduloblastoma \u00e9 integrar o trabalho de v\u00e1rios laborat\u00f3rios, com foco absoluto no meduloblastoma do Grupo 4. Esta \u00e9 a proposta do Cons\u00f3rcio Cure Group 4, viabilizada pela The Medulloblastoma Initiative, a MBI.<\/p>

Esse tipo de pesquisa ampla e colaborativa recebeu muito pouco financiamento at\u00e9 agora. Os laborat\u00f3rios do Cons\u00f3rcio Cure Group 4 se comprometem a trabalhar juntos, compartilhar dados antes mesmo de serem publicados e acelerar o desenvolvimento de protocolos de tratamento eficazes, com o objetivo de desenvolver novas terapias em um prazo curto \u2014 um a dois anos \u2014 em vez dos cinco a dez anos que s\u00e3o normalmente esperados.<\/p>

Nos primeiros 6 meses de trabalho (iniciado em 2021), o Cons\u00f3rcio j\u00e1 implementou modelos inovadores e fez novas descobertas sobre o meduloblastoma do Grupo 4.<\/strong><\/span><\/p>

E, a partir de 2024, teremos os primeiros estudos cl\u00ednicos com crian\u00e7as. Vamos encontrar a cura!<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\u201cCom o apoio certo, ser\u00e1 poss\u00edvel alcan\u00e7ar uma abordagem terap\u00eautica muito mais rapidamente \u2014 18 a 24 meses, ao inv\u00e9s de 3 a 5 anos\u201d.<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Roger J. Packer, M. D.<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Diretor do Gilbert Neurofibromatosis Institute e do Brain Tumor
Institute do Children\u2019s National Hospital.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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INVESTIGADOR PRINCIPAL<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Dr. Roger J. Packer<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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O Dr. Roger J. Packer, idealizador e investigador principal do Cons\u00f3rcio Cure Group 4, \u00e9 um especialista mundial em pesquisa cl\u00ednica e cient\u00edfica em neuro-oncologia. Dr. Packer iniciou sua carreira de pesquisador em 1981 \u2014 desde ent\u00e3o, ele se dedicou intensamente a pesquisar o meduloblastoma, procurando identificar a causa do tumor, seu padr\u00e3o de dissemina\u00e7\u00e3o e identificar tratamentos mais eficazes para o meduloblastoma e outros tumores cerebrais pedi\u00e1tricos agressivos.<\/p>

Dr. Packer participou do primeiro estudo que demonstrou claramente que acrescentar a quimioterapia ao tratamento em crian\u00e7as com meduloblastoma tinha benef\u00edcios. O estudo contribuiu para aumentar a propor\u00e7\u00e3o de crian\u00e7as que sobrevivem ao meduloblastoma. Agora, o Dr. Packer lidera o Cons\u00f3rcio Cure Group 4, que tem como objetivo \u2014 com base em todo o conhecimento adquirido ao longo de 40 anos e com apoio financeiro da MBI \u2014 desvendar as bases moleculares e imunol\u00f3gicas do meduloblastoma e desenvolver rapidamente um novo tratamento terap\u00eautico.\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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TIME DA PESQUISA<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Conhe\u00e7a os principais pesquisadores<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Roger J. Packer<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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M.D., Children\u2019s National Hospital, Washington DC\n<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Eugene Hwang<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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M.D.,
\nChildren\u2019sNational Hospital<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Robert Wechsler-Reya<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Ph.D.,
Columbia University, New York<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Duane Mitchell<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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M.D., Ph.D.,
\nUniversity of Florida<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Nicholas Vitanza<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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M.D.,
Seattle Children's Hospital<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Jessica B. Foster<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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M.D.,
Children's Hospital\u00a0of\u00a0Philadelphia<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Michael Taylor<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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M.D., Ph.D.,
Texas Children\u2019s Hospital<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Vijay Ramaswamy<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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M.D., Ph.D.,\nSickKids, Toronto, Canada<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Yanxin Pei<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Ph.D.,
Children\u2019s National Hospital<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Brian Rood<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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M.D.,
Children\u2019s National Hospital Conrad<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Sheila Singh<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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M.D., Ph.D.,
McMaster University, Ontario, Canada<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Tobey MacDonald<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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M.D., Emory University School of Medicine, Atlanta<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Lena M. Kutscher<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Ph.D.,\nHeidelberg University, Germany<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Stefan Pfister<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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M.D.,
Heidelberg University, Germany<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Dalia Haydar<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Pharm.D., Ph.D.,
Children\u2019s National Hospital<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Javad Nazarian<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Ph.D.,
Children\u2019s National Hospital<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Carl Koschmann<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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M.D., University of Michigan<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Elias Sayour<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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M.D., PhD.,
University of Florida<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Craig Daniels<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Ph.D.,
SickKids Toronto<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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William Weiss<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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M.D., Ph.D.,
University of California\n\n<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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INSTITUI\u00c7\u00d5ES CIENT\u00cdFICAS\nINTEGRANTES DO CONS\u00d3RCIO<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Conselho consultivo independente<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Um Conselho Consultivo Independente, composto por quatro pesquisadores renomados.
Os marcos da pesquisa s\u00e3o auditados a cada tr\u00eas meses. Com total transpar\u00eancia, a Medulloblastoma Initiative fornece aos doadores relat\u00f3rios\nsemestrais que acompanham a evolu\u00e7\u00e3o do projeto.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Rajeev Vibhakar, MD, PhD, MPH\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Hospital Infantil Colorado, Universidade do Colorado

\n\nProfessor de Hematologia\/Oncologia e Transplante de medula \u00f3ssea, atua\u00e7\u00e3o cl\u00ednica com \u00eanfase no tratamento do meduloblastoma. \n

\nEst\u00e1 envolvido em pesquisas de ponta, focando nos mecanismos gen\u00e9ticos que transformam c\u00e9lulas cerebrais normais em cancer\u00edgenas, e como essas altera\u00e7\u00f5es podem melhorar o diagn\u00f3stico e tratamento de tumores cerebrais.\n<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Scott Pomeroy, MD, PhD\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Hospital Infantil de Boston, Escola de Medicina de Harvard

\n\nChefe do Departamento de Neurologia, professor de Neurologia na Escola de Medicina de Harvard.\n\n

\n\nEle desempenhou um papel fundamental na cria\u00e7\u00e3o de protocolos de tratamento para crian\u00e7as com tumores cerebrais, e no incentivo \u00e0 colabora\u00e7\u00e3o entre institui\u00e7\u00f5es de pesquisa, visando melhorar o cuidado e os resultados dos pacientes.\n<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Sidnei Epelman, MD\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Casa de Sa\u00fade Santa Marcelina, S\u00e3o Paulo, Brasil

\n\nOncopediatra, Presidente da Associa\u00e7\u00e3o para Crian\u00e7as e Adolescentes com C\u00e2ncer (TUCCA). Diretor do Departamento de Oncologia Pedi\u00e1trica, Hospital Santa Marcelina. Professor de Oncologia Cl\u00ednica, Faculdade Santa Marcelina.\n\n

\n\nCoordenador do Grupo Cooperativo de Tumores do Sistema Nervoso Central da Sociedade Brasileira de Oncologia Pedi\u00e1trica (SOBOPE), e presidente latinoamericano do International Network for Cancer and Treatment Research (INCTR).<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Stewart Goldman, MD\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Hospital Infantil Phoenix, Universidade do Arizona

\n\nOncologista Pedi\u00e1trico no Phoenix Children's Hospital, professor na Faculdade de Medicina da Universidade do Arizona, recebeu v\u00e1rias premia\u00e7\u00f5es em sua carreira.\n\n

\n\nEle est\u00e1 ativamente envolvido em ensaios cl\u00ednicos, sendo pioneiro em novas terapias para melhorar a sobreviv\u00eancia e a qualidade de vida dos pacientes.<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Juntos fazendo hist\u00f3ria<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Em menos de 30 meses ap\u00f3s sua funda\u00e7\u00e3o, a MBI alcan\u00e7ou um de seus objetivos mais importantes. Isso abriu portas para dois novos ensaios cl\u00ednicos aprovados pela FDA sobre poss\u00edveis tratamentos para recidiva de meduloblastoma do Grupo 4. Ambos s\u00e3o liderados por investigadores da Universidade da Fl\u00f3rida e financiados pela MBI. Cada um representa o primeiro teste desse tipo em humanos.<\/p>

Leia os detalhes no Report de Setembro 2024<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tFA\u00c7A O DOWNLOAD<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"\"\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

Meet the Medulloblastoma Cure Research Network, supported by The Medulloblastoma Initiative, connecting scientists with solutions.<\/p>","protected":false},"author":1,"featured_media":3154,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-192","page","type-page","status-publish","has-post-thumbnail","hentry"],"yoast_head":"\nMB Cure Research Network | The Medulloblastoma Initiative<\/title>\n<meta name=\"description\" content=\"Meet the Medulloblastoma Cure Research Network, supported by The Medulloblastoma Initiative, connecting scientists with solutions.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mbinitiative.org\/pt\/rede-de-pesquisa-2\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" 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